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Forty-five of 264 (17%) patients receiving tizanidine and 13 of 261 (5%) of patients receiving placebo in three multiple dose, placebo-controlled clinical studies, discontinued treatment for adverse events.

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The only thing that my state did was make it a substance controlled medication where I had to sign a contract with my MD to where I am not receiving any type of other muscle relaxant from any other dr, and get a test done to make sure its in my system.

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